KEGG interactome

Source: R/keggInteractome.R

Interactome generated by merging KEGG pathways extracted using the ROntoTools R package (update: Jan, 2025).

kegg

Format

"kegg" is an igraph network object of 4910 nodes and 45200 edges corresponding to the union of 231 KEGG pathways.

References

Kanehisa M, Goto S (1999). KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acid Research 28(1): 27-30. <https://doi.org/10.1093/nar/27.1.29>

Calin Voichita, Sahar Ansari and Sorin Draghici (2023). ROntoTools: R Onto-Tools suite. R package version 2.30.0.

Examples


# KEGG graph
summary(kegg)
#> IGRAPH f132c7d DN-- 4910 45200 -- 
#> + attr: name (v/c)

# KEGG degrees of freedom
vcount(kegg)*(vcount(kegg) - 1)/2 - ecount(kegg)
#> [1] 12006395